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All manufacturers ACI Ltd. Rabeprazole is a proton pump inhibitor. This product is not sold individually. You must select at least 1 quantity for this product.
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Anril SR Anril spray. Rabeprazole suppresses gastric acid secretion by inhibiting the gastric. It blocks the final step of gastric acid secretion.
Following oral administration of 20 mg, rabeprazole is absorbed and can be detected in plasma by 1 hour. The effects of food on the absorption of rabeprazole have not been evaluated.
Rabeprazole is Rabeprazole is primarily metabolized in the liver by cytochromes P 3A sulphone metabolite and 2C19 desmethyl- Rabeprazole.
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The remainder of the dose is recovered in the faeces. Healing of erosive or ulcerative gastro-esophageal reflux disease; Maintenance of healing of erosive or ulcerative gastro-esophageal reflux disease; Benign gastric ulcer; Healing of duodenal ulcer; Treatment of pathological hypersecretory conditions, including Zollinger-Ellison Syndrome.
Healing of erosive or ulcerative gastro-esophageal reflux disease GERD : 20 mg once daily in the morning for weeks. For those patients who have not been healed after 8 weeks of treatment, an additional 8-week course may be considered.
Maintenance of healing of erosive or ulcerative gastroesophageal reflux disease: 20 mg once daily in the morning. Benign gastric ulcer: 20 mg once daily in the morning for 6 weeks, followed by a further 6 weeks if not fully healed.
Healing of duodenal ulcer: 20 mg once daily in the morning for a period upto 4 weeks. A few patients may require additional therapy to achieve healing.
Pathological hypersecretory conditions including Zollinger-Ellison Syndrome: The recommended adult oral starting dose is 60 mg daily.
Doses should be adjusted to individual patient needs and should be continued as long as clinically indicated. Some patients may require divided doses.
Dry mouth, gastrointestinal disturbances including diarrhoea, nausea and vomiting, constipation, flatulence, abdominal painliver dysfunction, taste disturbance, hypersensitivity reactions including rash, urticaria, angioedema, bronchospasm, anaphylaxisperipheral oedema, depression, dizziness, drowsiness, headache, insomnia, fever, haematological changes including agranulocytosis, leucocytosis, leucopenia, pancytopenia, thrombocytopeniainterstitial nephritis, muscle and joint pain, blurred vision, photosensitivity, pruritus, severe skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous eruptionsweating, malaise.
Proton pump inhibitors decrease gastric acidity and may increase the risk of gastro-intestinal infections, cough, pharyngitis, rhinitis, asthenia, influenza-like syndrome; less commonly chest pain, sinusitis, nervousness, rarely stomatitis, encephalopathy in severe liver disease, anorexia, weight gain.
There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. A decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
The safety and effectiveness of rabeprazole in paediatric patients have not been established. Known hypersensitivity to rabeprazole, substituted benzimidazoles or any component of the formulation.
Administration of rabeprazole to patients with mild to moderate liver impairment resulted in increased exposure and decreased elimination.
Caution should be exercised in patients with severe hepatic impairment. Rabeprazole is metabolized by the cytochrome P CYP drug metabolizing enzyme system.
Rabeprazole does not have clinically significant interactions with other drugs metabolized by the CYP system, such as warfarin and theophylline given as single oral dose, diazepam as a single intravenous dose, and phenytoin given as a single intravenous dose.
There has been no experience with large overdoses with rabeprazole. No specific antidote for rabeprazole is known. Rabeprazole is extensively protein bound and is not readily dialyzable.
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In the event of overdosage, treatment should be symptomatic and supportive. Store in a cool and dry place, protected from light.
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Manufacturers ACI Ltd. View full size. Manufacturer : Opsonin Pharma Ltd. Reference: Quantity: This product is not sold individually.
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Amodis 60ml Amodis Anadol SR Anadol Angilock 25 mg Angilock Angivent MR Anleptic Anoxa 10 Anril 0. Anril spray Ansulin Composition Finix? Pharmacokinetics Following oral administration of 20 mg, rabeprazole is absorbed and can be detected in plasma by 1 hour.
Indications Healing of erosive or ulcerative gastro-esophageal reflux disease; Maintenance of healing of erosive or ulcerative gastro-esophageal reflux disease; Benign gastric ulcer; Healing of duodenal ulcer; Treatment of pathological hypersecretory conditions, including Zollinger-Ellison Syndrome.
Side effects Dry mouth, gastrointestinal disturbances including diarrhoea, nausea and vomiting, constipation, flatulence, abdominal painliver dysfunction, taste disturbance, hypersensitivity reactions including rash, urticaria, angioedema, bronchospasm, anaphylaxisperipheral oedema, depression, dizziness, drowsiness, headache, insomnia, fever, haematological changes including agranulocytosis, leucocytosis, leucopenia, pancytopenia, thrombocytopeniainterstitial nephritis, muscle and joint pain, blurred vision, photosensitivity, pruritus, severe skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous eruptionsweating, malaise.
Contraindications Known hypersensitivity to rabeprazole, substituted benzimidazoles or any component of the formulation. Precautions Administration of rabeprazole to patients with mild to moderate liver impairment resulted in increased exposure and decreased elimination.
Drug interactions Rabeprazole is metabolized by the cytochrome P CYP drug metabolizing enzyme system. Overdosage There has been no experience with large overdoses with rabeprazole.
Storage Store in a cool and dry place, protected from light. Packaging Finix? After saving your customized product, remember to add it to your cart.
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